About Help FAQ

Symbol
Name
ID

Sppl2a
signal peptide peptidase like 2A
MGI:1913802

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

decreased activation-induced B cell apoptosis

decreased B cell proliferation

abnormal class switch recombination

decreased transitional stage T2 B cell number

decreased transitional stage T3 B cell number

abnormal transitional stage B cell morphology

arrested B cell differentiation

decreased myeloid dendritic cell number

decreased plasmacytoid dendritic cell number

decreased mature B cell number

decreased B-1 B cell number

decreased B-2 B cell number

decreased follicular B cell number

decreased marginal zone B cell number

decreased B cell number

decreased T cell number

abnormal mature B cell morphology

small spleen

abnormal B cell physiology

abnormal immunoglobulin level

decreased IgA level

decreased IgG1 level

decreased IgG2a level

decreased IgG2b level

decreased IgG3 level

decreased IgG level

decreased IgM level

Availability

Mouse Genotype

Sppl2a^chompB/Sppl2a^chompB

Sppl2a^m1Anu/Sppl2a^m1Anu

*

Sppl2a^m1Btlr/Sppl2a^m1Btlr

Sppl2a^m2Btlr/Sppl2a^m2Btlr

Sppl2a^tm1Basc/Sppl2a^tm1Basc

Sppl2a^tm1Dgen/Sppl2a^tm1Dgen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23